BDBM345449 1-[1-(2-chlorophenyl)sulfonyl-4,5-dihydroimidazol-2-yl]-4-ethyl-piperazine::US10202354, Example 114

SMILES CCN1CCN(CC1)C1=NCCN1S(=O)(=O)c1ccccc1Cl

InChI Key InChIKey=AZGZFUMVKNDZIP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345449   

TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM345449(1-[1-(2-chlorophenyl)sulfonyl-4,5-dihydroimidazol-...)
Affinity DataIC50:  2.81nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent