BDBM345588 5-[2-(2-Chloro-6-methyl-phenoxy)- 6-methanesulfonyl-pyrimidin-4-yl]- 1,3-dimethyl-1H-pyridin-2-one::US10202360, Example 133

SMILES Cc1cccc(C#N)c1Oc1nc(cc(n1)S(C)(=O)=O)-c1cc(C)c(=O)n(C)c1

InChI Key InChIKey=OJHRNTFYJMBKFW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345588   

TargetCREB-binding protein(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM345588(5-[2-(2-Chloro-6-methyl-phenoxy)- 6-methanesulfony...)
Affinity DataIC50: <500nMAssay Description:Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent