BDBM345762 (R)-5-[2-(2-Fluoro-6-methyl- phenoxy)-6-(1,2,3,4-tetrahydro- naphthalen-1-ylamino)-pyrimidin-4- yl]-1-methyl-1H-pyridin-2-one::US10202360, Example 307

SMILES Cc1cccc(F)c1Oc1nc(N[C@@H]2CCCc3ccccc23)cc(n1)-c1ccc(=O)n(C)c1

InChI Key InChIKey=GOILPEPQTUKABY-JOCHJYFZSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345762   

TargetCREB-binding protein(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM345762((R)-5-[2-(2-Fluoro-6-methyl- phenoxy)-6-(1,2,3,4-t...)
Affinity DataIC50: <500nMAssay Description:Determination of the IC50 for the CREBBP inhibitors disclosed herein was performed as follows: CREBBP was cloned and expressed in E. Coli as His-tag ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent