BDBM345836 US10202365, Compound 13::US10774070, Compound 13

SMILES CCOc1ccc(CNC(=O)c2ncc(cc2C)-c2nc(C)cc(Nc3cc(C)[nH]n3)n2)cc1

InChI Key InChIKey=XRIAOAWOBFARBL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 345836   

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Blueprint Medicines

US Patent
LigandPNGBDBM345836(US10202365, Compound 13 | US10774070, Compound 13)
Affinity DataIC50:  55nMAssay Description:In each well of a 384-well plate, 7.5 nM-10 nM of wild type RET (ProQinase 1090-0000-1) is incubated in a total of 12.5 μL of buffer (100 mM HEP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Blueprint Medicines

US Patent
LigandPNGBDBM345836(US10202365, Compound 13 | US10774070, Compound 13)
Affinity DataIC50:  55nMAssay Description:In each well of a 384-well plate, 7.5 nM-10 nM of wild type RET (ProQinase 1090-0000-1) is incubated in a total of 12.5 μL of buffer (100 mM HEP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent