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BDBM346047 4-[2-(6-Methyl-2-m- tolyl-3H- benzoimidazol-5- ylamino)-thiazol-4- yl]-benzonitrile::US10202370, Example 074

SMILES: Cc1cccc(c1)-c1nc2cc(C)c(Nc3nc(cs3)-c3ccc(cc3)C#N)cc2[nH]1

InChI Key:

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 346047   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM346047
PNG
(4-[2-(6-Methyl-2-m- tolyl-3H- benzoimidazol-5- yla...)
Show SMILES Cc1cccc(c1)-c1nc2cc(C)c(Nc3nc(cs3)-c3ccc(cc3)C#N)cc2[nH]1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a<1.00E+3n/an/an/an/a



AB SCIENCE

US Patent


Assay Description
Colorimetric cell proliferation and viability assay (reagent CellTiter-Blue purchased from Promega cat NG8081) was performed on BaF3 Kit WT cell lin...


US Patent US10202370 (2019)

More data for this
Ligand-Target Pair