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BDBM346051 US10202370, Example 081::[2-(3-Difluoromethyl- phenyl)-1,6- dimethyl-1H- benzoimidazol-5-yl]- (4-pyridin-4-yl- thiazol-2-yl)-amine

SMILES: Cc1cc2n(C)c(nc2cc1Nc1nc(cs1)-c1ccncc1)-c1cccc(c1)C(F)F

InChI Key: InChIKey=BMAAIFIWDHRUCW-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 346051   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM346051
PNG
(US10202370, Example 081 | [2-(3-Difluoromethyl- ph...)
Show SMILES Cc1cc2n(C)c(nc2cc1Nc1nc(cs1)-c1ccncc1)-c1cccc(c1)C(F)F
Show InChI InChI=1S/C24H19F2N5S/c1-14-10-21-19(28-23(31(21)2)17-5-3-4-16(11-17)22(25)26)12-18(14)29-24-30-20(13-32-24)15-6-8-27-9-7-15/h3-13,22H,1-2H3,(H,29,30)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a<1.00E+3n/an/an/an/a



AB SCIENCE

US Patent


Assay Description
Colorimetric cell proliferation and viability assay (reagent CellTiter-Blue purchased from Promega cat NG8081) was performed on BaF3 Kit WT cell lin...


US Patent US10202370 (2019)

More data for this
Ligand-Target Pair