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BDBM346053 US10202370, Example 083::[1,6-Dimethyl-2-(3- trifluoromethoxy- phenyl)-1H- benzoimidazol-5-yl]- (4-pyridin-4-yl- thiazol-2-yl)-amine

SMILES: Cc1cc2n(C)c(nc2cc1Nc1nc(cs1)-c1ccncc1)-c1cccc(OC(F)(F)F)c1

InChI Key: InChIKey=UZXXCHHFCKHKPE-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 346053   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM346053
PNG
(US10202370, Example 083 | [1,6-Dimethyl-2-(3- trif...)
Show SMILES Cc1cc2n(C)c(nc2cc1Nc1nc(cs1)-c1ccncc1)-c1cccc(OC(F)(F)F)c1
Show InChI InChI=1S/C24H18F3N5OS/c1-14-10-21-19(12-18(14)30-23-31-20(13-34-23)15-6-8-28-9-7-15)29-22(32(21)2)16-4-3-5-17(11-16)33-24(25,26)27/h3-13H,1-2H3,(H,30,31)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a<1.00E+3n/an/an/an/a



AB SCIENCE

US Patent


Assay Description
Colorimetric cell proliferation and viability assay (reagent CellTiter-Blue purchased from Promega cat NG8081) was performed on BaF3 Kit WT cell lin...


US Patent US10202370 (2019)

More data for this
Ligand-Target Pair