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BDBM346062 US10202370, Example 100::[2-(3-Difluoromethyl- phenyl)-1-isopropyl- 6-methyl-1H- benzoimidazol-5-yl]- (4-pyridin-4-yl- thiazol-2-yl)-amine

SMILES: CC(C)n1c(nc2cc(Nc3nc(cs3)-c3ccncc3)c(C)cc12)-c1cccc(c1)C(F)F

InChI Key: InChIKey=PIOAHFWWENRHTB-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 346062   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM346062
PNG
(US10202370, Example 100 | [2-(3-Difluoromethyl- ph...)
Show SMILES CC(C)n1c(nc2cc(Nc3nc(cs3)-c3ccncc3)c(C)cc12)-c1cccc(c1)C(F)F
Show InChI InChI=1S/C26H23F2N5S/c1-15(2)33-23-11-16(3)20(31-26-32-22(14-34-26)17-7-9-29-10-8-17)13-21(23)30-25(33)19-6-4-5-18(12-19)24(27)28/h4-15,24H,1-3H3,(H,31,32)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a<1.00E+3n/an/an/an/a



AB SCIENCE

US Patent


Assay Description
Colorimetric cell proliferation and viability assay (reagent CellTiter-Blue purchased from Promega cat NG8081) was performed on BaF3 Kit WT cell lin...


US Patent US10202370 (2019)

More data for this
Ligand-Target Pair