BindingDB logo
myBDB logout

BDBM346063 US10202370, Example 101::[1-Isopropyl-6- methyl-2-(3- trifluoromethyl- phenyl)-1H- benzoimidazol-5-yl]- (4-pyridin-4-yl- thiazol-2-yl)-amine

SMILES: CC(C)n1c(nc2cc(Nc3nc(cs3)-c3ccncc3)c(C)cc12)-c1cccc(c1)C(F)(F)F

InChI Key: InChIKey=UENKPGFLSLACJF-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 346063   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM346063
PNG
(US10202370, Example 101 | [1-Isopropyl-6- methyl-2...)
Show SMILES CC(C)n1c(nc2cc(Nc3nc(cs3)-c3ccncc3)c(C)cc12)-c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C26H22F3N5S/c1-15(2)34-23-11-16(3)20(32-25-33-22(14-35-25)17-7-9-30-10-8-17)13-21(23)31-24(34)18-5-4-6-19(12-18)26(27,28)29/h4-15H,1-3H3,(H,32,33)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a<1.00E+3n/an/an/an/a



AB SCIENCE

US Patent


Assay Description
Colorimetric cell proliferation and viability assay (reagent CellTiter-Blue purchased from Promega cat NG8081) was performed on BaF3 Kit WT cell lin...


US Patent US10202370 (2019)

More data for this
Ligand-Target Pair