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BDBM346064 (1-Isopropyl-6- methyl-2-m-tolyl-1H- benzoimidazol-5-yl)- (4-pyridin-4-yl- thiazol-2-yl)-amine::US10202370, Example 102

SMILES: CC(C)n1c(nc2cc(Nc3nc(cs3)-c3ccncc3)c(C)cc12)-c1cccc(C)c1

InChI Key: InChIKey=FTRBWOOTAUHLCL-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 346064   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM346064
PNG
((1-Isopropyl-6- methyl-2-m-tolyl-1H- benzoimidazol...)
Show SMILES CC(C)n1c(nc2cc(Nc3nc(cs3)-c3ccncc3)c(C)cc12)-c1cccc(C)c1
Show InChI InChI=1S/C26H25N5S/c1-16(2)31-24-13-18(4)21(14-22(24)28-25(31)20-7-5-6-17(3)12-20)29-26-30-23(15-32-26)19-8-10-27-11-9-19/h5-16H,1-4H3,(H,29,30)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a<1.00E+3n/an/an/an/a



AB SCIENCE

US Patent


Assay Description
Colorimetric cell proliferation and viability assay (reagent CellTiter-Blue purchased from Promega cat NG8081) was performed on BaF3 Kit WT cell lin...


US Patent US10202370 (2019)

More data for this
Ligand-Target Pair