BindingDB logo
myBDB logout

BDBM346065 US10202370, Example 103::[2-(3-Difluoromethyl- phenyl)-1-ethyl-6- methyl-1H- benzoimidazol-5-yl- (4-pyridin-4-yl- thiazol-2-yl)-amine

SMILES: CCn1c(nc2cc(Nc3nc(cs3)-c3ccncc3)c(C)cc12)-c1cccc(c1)C(F)F

InChI Key: InChIKey=ZFIUHWTZJPMQKN-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 346065   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM346065
PNG
(US10202370, Example 103 | [2-(3-Difluoromethyl- ph...)
Show SMILES CCn1c(nc2cc(Nc3nc(cs3)-c3ccncc3)c(C)cc12)-c1cccc(c1)C(F)F
Show InChI InChI=1S/C25H21F2N5S/c1-3-32-22-11-15(2)19(30-25-31-21(14-33-25)16-7-9-28-10-8-16)13-20(22)29-24(32)18-6-4-5-17(12-18)23(26)27/h4-14,23H,3H2,1-2H3,(H,30,31)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a<1.00E+3n/an/an/an/a



AB SCIENCE

US Patent


Assay Description
Colorimetric cell proliferation and viability assay (reagent CellTiter-Blue purchased from Promega cat NG8081) was performed on BaF3 Kit WT cell lin...


US Patent US10202370 (2019)

More data for this
Ligand-Target Pair