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BDBM346067 US10202370, Example 105::[1-Ethyl-6-methyl-2- (3-trifluoromethyl- phenyl)-1H- benzoimidazol-5-yl]- (4-pyridin-4-yl- thiazol-2-yl)-amine

SMILES: CCn1c(nc2cc(Nc3nc(cs3)-c3ccncc3)c(C)cc12)-c1cccc(c1)C(F)(F)F

InChI Key: InChIKey=WZPVDURRZYKUAS-UHFFFAOYSA-N

Data: 1 EC50

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 346067   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM346067
PNG
(US10202370, Example 105 | [1-Ethyl-6-methyl-2- (3-...)
Show SMILES CCn1c(nc2cc(Nc3nc(cs3)-c3ccncc3)c(C)cc12)-c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C25H20F3N5S/c1-3-33-22-11-15(2)19(31-24-32-21(14-34-24)16-7-9-29-10-8-16)13-20(22)30-23(33)17-5-4-6-18(12-17)25(26,27)28/h4-14H,3H2,1-2H3,(H,31,32)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a<1.00E+3n/an/an/an/a



AB SCIENCE

US Patent


Assay Description
Colorimetric cell proliferation and viability assay (reagent CellTiter-Blue purchased from Promega cat NG8081) was performed on BaF3 Kit WT cell lin...


US Patent US10202370 (2019)

More data for this
Ligand-Target Pair