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BDBM346074 4-[2-(1,6-Dimethyl-2- m-tolyl-1H- benzoimidazol-5- ylamino)-thiazol-4- yl]-benzonitrile::US10202370, Example 112

SMILES: Cc1cccc(c1)-c1nc2cc(Nc3nc(cs3)-c3ccc(cc3)C#N)c(C)cc2n1C

InChI Key: InChIKey=SFVVCUYHFZNREN-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 346074   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM346074
PNG
(4-[2-(1,6-Dimethyl-2- m-tolyl-1H- benzoimidazol-5-...)
Show SMILES Cc1cccc(c1)-c1nc2cc(Nc3nc(cs3)-c3ccc(cc3)C#N)c(C)cc2n1C
Show InChI InChI=1S/C26H21N5S/c1-16-5-4-6-20(11-16)25-28-22-13-21(17(2)12-24(22)31(25)3)29-26-30-23(15-32-26)19-9-7-18(14-27)8-10-19/h4-13,15H,1-3H3,(H,29,30)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a<1.00E+3n/an/an/an/a



AB SCIENCE

US Patent


Assay Description
Colorimetric cell proliferation and viability assay (reagent CellTiter-Blue purchased from Promega cat NG8081) was performed on BaF3 Kit WT cell lin...


US Patent US10202370 (2019)

More data for this
Ligand-Target Pair