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BDBM346077 US10202370, Example 119::[4-(2-Chloro-pyridin- 4-yl)-thiazol-2-yl]-[2- (3-difluoromethyl- phenyl)-1,6- dimethyl-1H- benzoimidazol-5-yl]- amine

SMILES: Cc1cc2n(C)c(nc2cc1Nc1nc(cs1)-c1ccnc(Cl)c1)-c1cccc(c1)C(F)F

InChI Key: InChIKey=YQZSAMDSAMHWFV-UHFFFAOYSA-N

Data: 1 EC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 346077   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM346077
PNG
(US10202370, Example 119 | [4-(2-Chloro-pyridin- 4-...)
Show SMILES Cc1cc2n(C)c(nc2cc1Nc1nc(cs1)-c1ccnc(Cl)c1)-c1cccc(c1)C(F)F
Show InChI InChI=1S/C24H18ClF2N5S/c1-13-8-20-18(29-23(32(20)2)16-5-3-4-15(9-16)22(26)27)11-17(13)30-24-31-19(12-33-24)14-6-7-28-21(25)10-14/h3-12,22H,1-2H3,(H,30,31)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a<1.00E+3n/an/an/an/a



AB SCIENCE

US Patent


Assay Description
Colorimetric cell proliferation and viability assay (reagent CellTiter-Blue purchased from Promega cat NG8081) was performed on BaF3 Kit WT cell lin...


US Patent US10202370 (2019)

More data for this
Ligand-Target Pair