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BDBM346078 US10202370, Example 120::[2-(3- Methanesulfonyl- phenyl)-1,6- dimethyl-1H- benzoimidazol-5-yl]- (4-pyridin-4-yl- thiazol-2-yl)-amine

SMILES: Cc1cc2n(C)c(nc2cc1Nc1nc(cs1)-c1ccncc1)-c1cccc(c1)S(C)(=O)=O

InChI Key: InChIKey=WRHRTMMDSAWUDS-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 346078   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM346078
PNG
(US10202370, Example 120 | [2-(3- Methanesulfonyl- ...)
Show SMILES Cc1cc2n(C)c(nc2cc1Nc1nc(cs1)-c1ccncc1)-c1cccc(c1)S(C)(=O)=O
Show InChI InChI=1S/C24H21N5O2S2/c1-15-11-22-20(26-23(29(22)2)17-5-4-6-18(12-17)33(3,30)31)13-19(15)27-24-28-21(14-32-24)16-7-9-25-10-8-16/h4-14H,1-3H3,(H,27,28)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a<1.00E+3n/an/an/an/a



AB SCIENCE

US Patent


Assay Description
Colorimetric cell proliferation and viability assay (reagent CellTiter-Blue purchased from Promega cat NG8081) was performed on BaF3 Kit WT cell lin...


US Patent US10202370 (2019)

More data for this
Ligand-Target Pair