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BDBM346114 US10202370, Example 009::{6-Methyl-2-[4-(4- methyl-piperazin-1- ylmethyl)-phenyl]- 3H-benzoimidazol-5- yl}-(4-pyridin-3-yl- pyrimidin-2-yl)- amine

SMILES: CN1CCN(Cc2ccc(cc2)-c2nc3cc(C)c(Nc4nccc(n4)-c4cccnc4)cc3[nH]2)CC1

InChI Key:

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 346114   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM346114
PNG
(US10202370, Example 009 | {6-Methyl-2-[4-(4- methy...)
Show SMILES CN1CCN(Cc2ccc(cc2)-c2nc3cc(C)c(Nc4nccc(n4)-c4cccnc4)cc3[nH]2)CC1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 5.50E+3n/an/an/an/a



AB SCIENCE

US Patent


Assay Description
Colorimetric cell proliferation and viability assay (reagent CellTiter-Blue purchased from Promega cat NG8081) was performed on BaF3 Kit WT cell lin...


US Patent US10202370 (2019)

More data for this
Ligand-Target Pair