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BDBM346157 US10202370, Example 091::[1-Methyl-2-(3- trifluoromethyl- phenyl)-1H- benzoimidazol-5-yl]- (4-pyridin-3-yl- thiazol-2-yl)-amine

SMILES: Cn1c(nc2cc(Nc3nc(cs3)-c3cccnc3)ccc12)-c1cccc(c1)C(F)(F)F

InChI Key: InChIKey=HSJLPKBVUSJVRX-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 346157   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM346157
PNG
(US10202370, Example 091 | [1-Methyl-2-(3- trifluor...)
Show SMILES Cn1c(nc2cc(Nc3nc(cs3)-c3cccnc3)ccc12)-c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C23H16F3N5S/c1-31-20-8-7-17(28-22-30-19(13-32-22)15-5-3-9-27-12-15)11-18(20)29-21(31)14-4-2-6-16(10-14)23(24,25)26/h2-13H,1H3,(H,28,30)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 5.50E+3n/an/an/an/a



AB SCIENCE

US Patent


Assay Description
Colorimetric cell proliferation and viability assay (reagent CellTiter-Blue purchased from Promega cat NG8081) was performed on BaF3 Kit WT cell lin...


US Patent US10202370 (2019)

More data for this
Ligand-Target Pair