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BDBM346159 US10202370, Example 095::{1,6-Dimethyl-2-[3- (4-methyl-piperazin- 1-yl)-phenyl]-1H- benzoimidazol-5-yl}- (4-pyridin-3-yl- thiazol-2-yl)-amine

SMILES: CN1CCN(CC1)c1cccc(c1)-c1nc2cc(Nc3nc(cs3)-c3cccnc3)c(C)cc2n1C

InChI Key: InChIKey=SOUJVPJQDRIUDA-UHFFFAOYSA-N

Data: 1 EC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 346159   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM346159
PNG
(US10202370, Example 095 | {1,6-Dimethyl-2-[3- (4-m...)
Show SMILES CN1CCN(CC1)c1cccc(c1)-c1nc2cc(Nc3nc(cs3)-c3cccnc3)c(C)cc2n1C
Show InChI InChI=1S/C28H29N7S/c1-19-14-26-24(16-23(19)31-28-32-25(18-36-28)21-7-5-9-29-17-21)30-27(34(26)3)20-6-4-8-22(15-20)35-12-10-33(2)11-13-35/h4-9,14-18H,10-13H2,1-3H3,(H,31,32)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 5.50E+3n/an/an/an/a



AB SCIENCE

US Patent


Assay Description
Colorimetric cell proliferation and viability assay (reagent CellTiter-Blue purchased from Promega cat NG8081) was performed on BaF3 Kit WT cell lin...


US Patent US10202370 (2019)

More data for this
Ligand-Target Pair