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BDBM346161 US10202370, Example 098::{1,6-Dimethyl-2-[4- (4-methyl-piperazin- 1-ylmethyl)-phenyl]- 1H-benzoimidazol-5- yl}-(4-pyridin-3-yl- thiazol-2-yl)-amine

SMILES: CN1CCN(Cc2ccc(cc2)-c2nc3cc(Nc4nc(cs4)-c4cccnc4)c(C)cc3n2C)CC1

InChI Key: InChIKey=XNALZDKDDGDVTB-UHFFFAOYSA-N

Data: 1 EC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 346161   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM346161
PNG
(US10202370, Example 098 | {1,6-Dimethyl-2-[4- (4-m...)
Show SMILES CN1CCN(Cc2ccc(cc2)-c2nc3cc(Nc4nc(cs4)-c4cccnc4)c(C)cc3n2C)CC1
Show InChI InChI=1S/C29H31N7S/c1-20-15-27-25(16-24(20)32-29-33-26(19-37-29)23-5-4-10-30-17-23)31-28(35(27)3)22-8-6-21(7-9-22)18-36-13-11-34(2)12-14-36/h4-10,15-17,19H,11-14,18H2,1-3H3,(H,32,33)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 5.50E+3n/an/an/an/a



AB SCIENCE

US Patent


Assay Description
Colorimetric cell proliferation and viability assay (reagent CellTiter-Blue purchased from Promega cat NG8081) was performed on BaF3 Kit WT cell lin...


US Patent US10202370 (2019)

More data for this
Ligand-Target Pair