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BDBM346164 US10202370, Example 116::[3,6-Dimethyl-2-(3- trifluoromethyl- phenyl)-3H- benzoimidazol-5-yl]- (4-pyridin-3-yl- thiazol-2-yl)-amine

SMILES: Cc1cc2nc(-c3cccc(c3)C(F)(F)F)n(C)c2cc1Nc1nc(cs1)-c1cccnc1

InChI Key: InChIKey=XSUKQKMPHRLWMM-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 346164   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM346164
PNG
(US10202370, Example 116 | [3,6-Dimethyl-2-(3- trif...)
Show SMILES Cc1cc2nc(-c3cccc(c3)C(F)(F)F)n(C)c2cc1Nc1nc(cs1)-c1cccnc1
Show InChI InChI=1S/C24H18F3N5S/c1-14-9-19-21(32(2)22(29-19)15-5-3-7-17(10-15)24(25,26)27)11-18(14)30-23-31-20(13-33-23)16-6-4-8-28-12-16/h3-13H,1-2H3,(H,30,31)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 5.50E+3n/an/an/an/a



AB SCIENCE

US Patent


Assay Description
Colorimetric cell proliferation and viability assay (reagent CellTiter-Blue purchased from Promega cat NG8081) was performed on BaF3 Kit WT cell lin...


US Patent US10202370 (2019)

More data for this
Ligand-Target Pair