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BDBM346193 US10202373, Compound I-5::US10202373, Example 3T

SMILES: CC(=O)Nc1cc(ccn1)-c1cnc(C)c2n(cc(C)c12)S(C)(=O)=O

InChI Key: InChIKey=OTSFYRCRAZYOTC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 346193   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphatidylinositol 3-kinase catalytic subunit type 3


(Homo sapiens (Human))
BDBM346193
PNG
(US10202373, Compound I-5 | US10202373, Example 3T)
Show SMILES CC(=O)Nc1cc(ccn1)-c1cnc(C)c2n(cc(C)c12)S(C)(=O)=O
Show InChI InChI=1S/C17H18N4O3S/c1-10-9-21(25(4,23)24)17-11(2)19-8-14(16(10)17)13-5-6-18-15(7-13)20-12(3)22/h5-9H,1-4H3,(H,18,20,22)
PDB
MMDB

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KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 75n/an/an/an/an/an/a



MILLENNIUM PHARMACEUTICALS, INC.

US Patent


Assay Description
100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...


US Patent US10202373 (2019)

More data for this
Ligand-Target Pair