BindingDB logo
myBDB logout

BDBM346197 US10202373, Compound I-9::US10202373, Example 3J

SMILES: CS(=O)(=O)n1ccc2c(cncc12)-c1ccnc(Nc2ncco2)c1

InChI Key: InChIKey=AXWCNRNHFMYOTH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 346197   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphatidylinositol 3-kinase catalytic subunit type 3


(Homo sapiens (Human))
BDBM346197
PNG
(US10202373, Compound I-9 | US10202373, Example 3J)
Show SMILES CS(=O)(=O)n1ccc2c(cncc12)-c1ccnc(Nc2ncco2)c1
Show InChI InChI=1S/C16H13N5O3S/c1-25(22,23)21-6-3-12-13(9-17-10-14(12)21)11-2-4-18-15(8-11)20-16-19-5-7-24-16/h2-10H,1H3,(H,18,19,20)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 30n/an/an/an/an/an/a



MILLENNIUM PHARMACEUTICALS, INC.

US Patent


Assay Description
100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...


US Patent US10202373 (2019)

More data for this
Ligand-Target Pair