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BDBM346203 US10202373, Compound I-15::US10202373, Example 3X

SMILES: COC(=O)Nc1cc(ccn1)-c1cnc(C)c2n(ccc12)S(=O)(=O)CC(C)C

InChI Key: InChIKey=KDISNDAKCGRTGW-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 346203   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphatidylinositol 3-kinase catalytic subunit type 3


(Homo sapiens (Human))
BDBM346203
PNG
(US10202373, Compound I-15 | US10202373, Example 3X)
Show SMILES COC(=O)Nc1cc(ccn1)-c1cnc(C)c2n(ccc12)S(=O)(=O)CC(C)C
Show InChI InChI=1S/C19H22N4O4S/c1-12(2)11-28(25,26)23-8-6-15-16(10-21-13(3)18(15)23)14-5-7-20-17(9-14)22-19(24)27-4/h5-10,12H,11H2,1-4H3,(H,20,22,24)
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a<10n/an/an/an/an/an/a



MILLENNIUM PHARMACEUTICALS, INC.

US Patent


Assay Description
100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...


US Patent US10202373 (2019)

More data for this
Ligand-Target Pair