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BDBM346204 US10202373, Compound I-16::US10202373, Example 3M

SMILES: CCS(=O)(=O)n1ccc2c(cnc(C)c12)-c1ccnc(NC(C)=O)c1

InChI Key: InChIKey=RHKIYIFGCWPPLM-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 346204   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphatidylinositol 3-kinase catalytic subunit type 3


(Homo sapiens (Human))
BDBM346204
PNG
(US10202373, Compound I-16 | US10202373, Example 3M)
Show SMILES CCS(=O)(=O)n1ccc2c(cnc(C)c12)-c1ccnc(NC(C)=O)c1
Show InChI InChI=1S/C17H18N4O3S/c1-4-25(23,24)21-8-6-14-15(10-19-11(2)17(14)21)13-5-7-18-16(9-13)20-12(3)22/h5-10H,4H2,1-3H3,(H,18,20,22)
PDB
MMDB

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PC cid
PC sid
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US Patent
n/an/a<10n/an/an/an/an/an/a



MILLENNIUM PHARMACEUTICALS, INC.

US Patent


Assay Description
100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...


US Patent US10202373 (2019)

More data for this
Ligand-Target Pair