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BDBM346209 US10202373, Compound I-22::US10202373, Example 5

SMILES: CC(=O)Nc1cc(ccn1)-c1cncc2n(ncc12)S(=O)(=O)C1CC1

InChI Key: InChIKey=BZEJOQKYDGCRCE-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 346209   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphatidylinositol 3-kinase catalytic subunit type 3


(Homo sapiens (Human))
BDBM346209
PNG
(US10202373, Compound I-22 | US10202373, Example 5)
Show SMILES CC(=O)Nc1cc(ccn1)-c1cncc2n(ncc12)S(=O)(=O)C1CC1
Show InChI InChI=1S/C16H15N5O3S/c1-10(22)20-16-6-11(4-5-18-16)13-7-17-9-15-14(13)8-19-21(15)25(23,24)12-2-3-12/h4-9,12H,2-3H2,1H3,(H,18,20,22)
PDB
MMDB

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KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 75n/an/an/an/an/an/a



MILLENNIUM PHARMACEUTICALS, INC.

US Patent


Assay Description
100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...


US Patent US10202373 (2019)

More data for this
Ligand-Target Pair