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BDBM346212 US10202373, Compound I-25::US10202373, Example 10B

SMILES: CCOC(=O)Nc1cc(ccn1)-c1cncc2n(ccc12)S(C)(=O)=O

InChI Key: InChIKey=GRBJKGAJUQYWPI-UHFFFAOYSA-N

Data: 1 IC50

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 346212   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphatidylinositol 3-kinase catalytic subunit type 3


(Homo sapiens (Human))
BDBM346212
PNG
(US10202373, Compound I-25 | US10202373, Example 10...)
Show SMILES CCOC(=O)Nc1cc(ccn1)-c1cncc2n(ccc12)S(C)(=O)=O
Show InChI InChI=1S/C16H16N4O4S/c1-3-24-16(21)19-15-8-11(4-6-18-15)13-9-17-10-14-12(13)5-7-20(14)25(2,22)23/h4-10H,3H2,1-2H3,(H,18,19,21)
PDB
MMDB

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KEGG

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PC cid
PC sid
UniChem
US Patent
n/an/a<10n/an/an/an/an/an/a



MILLENNIUM PHARMACEUTICALS, INC.

US Patent


Assay Description
100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...


US Patent US10202373 (2019)

More data for this
Ligand-Target Pair