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BDBM346218 US10202373, Compound I-32::US10202373, Example 3U

SMILES: CS(=O)(=O)n1ccc2c(cncc12)-c1ccnc(N)c1

InChI Key: InChIKey=VRXIAUHRXQKUQB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 346218   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphatidylinositol 3-kinase catalytic subunit type 3


(Homo sapiens (Human))
BDBM346218
PNG
(US10202373, Compound I-32 | US10202373, Example 3U)
Show SMILES CS(=O)(=O)n1ccc2c(cncc12)-c1ccnc(N)c1
Show InChI InChI=1S/C13H12N4O2S/c1-20(18,19)17-5-3-10-11(7-15-8-12(10)17)9-2-4-16-13(14)6-9/h2-8H,1H3,(H2,14,16)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

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DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>100n/an/an/an/an/an/a



MILLENNIUM PHARMACEUTICALS, INC.

US Patent


Assay Description
100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...


US Patent US10202373 (2019)

More data for this
Ligand-Target Pair