BDBM346592 US10202378, Example 197::ethyl 4-[3-(3-carbamoylphenyl)-4,4,4-trifluoro-3-hydroxy-but-1-ynyl]-2,6-dimethyl-7-oxo-1H-pyrrolo[2,3-c]pyridine-3-carboxylate
SMILES CCOC(=O)c1c(C)[nH]c2c1c(cn(C)c2=O)C#CC(O)(c1cccc(c1)C(N)=O)C(F)(F)F
InChI Key
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 346592
TargetTranscription initiation factor TFIID subunit 1 [1381-1497](Homo sapiens (human))
Genentech
US Patent
Genentech
US Patent
Affinity DataIC50: 185nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
Genentech
US Patent
Genentech
US Patent
Affinity DataIC50: 34.1nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair