BDBM347045 4-amino-N-(3-chloro-4-fluorophenyl)-N′-hydroxy-1,2,5-oxadiazole-3-carboximidamide::US10202388, Ref. B

SMILES Nc1nonc1C(Nc1ccc(F)c(Cl)c1)=NO

InChI Key InChIKey=HGXSLPIXNPASGZ-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 347045   

TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Shanghai De Novo Pharmatech

US Patent
LigandPNGBDBM347045(4-amino-N-(3-chloro-4-fluorophenyl)-N′-hydro...)
Affinity DataIC50:  5.50E+4nMAssay Description:The TDO2 enzymatic assay was performed by UV absorption using a recombinant TDO2 and L-Tryptophan substrate. The UV absorption signal at 321 nm is co...More data for this Ligand-Target Pair
In DepthDetails US Patent