BDBM347363 US10301320, ID SW206979::US10869871, ID # SW206979::US20230285402, ID # SW206979::US9789116, SW206979
SMILES Nc1c(sc2nc(cc(-c3ccccc3)c12)-c1cccs1)C(O)=O
InChI Key InChIKey=YLAIQNSWCKTXRM-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 347363
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University
US Patent
Case Western Reserve University
US Patent
Affinity DataIC50: >7.50E+3nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH in an in vitro assay. More data for this Ligand-Target Pair
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University
US Patent
Case Western Reserve University
US Patent
Affinity DataIC50: >7.50E+3nMAssay Description:Inhibition of recombinant human C-terminal 6xHis-tagged 15-PGDH expressed in Escherichia coli using PGE2 as substrate after 15 mins in presence of NA...More data for this Ligand-Target Pair
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University
US Patent
Case Western Reserve University
US Patent
Affinity DataIC50: >7.50E+3nMAssay Description:This Example provides data on a group of structural analogues of SW033291. Data provided includes level of induction of a 15-PGDH-luciferase fusion g...More data for this Ligand-Target Pair