BDBM347363 US10301320, ID SW206979::US10869871, ID # SW206979::US20230285402, ID # SW206979::US9789116, SW206979

SMILES Nc1c(sc2nc(cc(-c3ccccc3)c12)-c1cccs1)C(O)=O

InChI Key InChIKey=YLAIQNSWCKTXRM-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 347363   

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM347363(US10301320, ID SW206979 | US10869871, ID # SW20697...)
Affinity DataIC50: >7.50E+3nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH in an in vitro assay. More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM347363(US10301320, ID SW206979 | US10869871, ID # SW20697...)
Affinity DataIC50: >7.50E+3nMAssay Description:Inhibition of recombinant human C-terminal 6xHis-tagged 15-PGDH expressed in Escherichia coli using PGE2 as substrate after 15 mins in presence of NA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM347363(US10301320, ID SW206979 | US10869871, ID # SW20697...)
Affinity DataIC50: >7.50E+3nMAssay Description:This Example provides data on a group of structural analogues of SW033291. Data provided includes level of induction of a 15-PGDH-luciferase fusion g...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent