BDBM347375 US10301320, ID SW208080::US10869871, ID # SW208080::US20230285402, ID # SW208080::US9789116, SW208080

SMILES CCCCCS(=O)c1sc2nc(cc(-c3ccccc3)c2c1N)-c1cccs1

InChI Key InChIKey=ASMAZLYZICSVTK-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 347375   

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM347375(US10301320, ID SW208080 | US10869871, ID # SW20808...)
Affinity DataIC50:  2.61nMAssay Description:Each compound for inhibiting enzymatic activity of recombinant 15-PGDH in an in vitro assay. More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM347375(US10301320, ID SW208080 | US10869871, ID # SW20808...)
Affinity DataIC50:  2.64nMAssay Description:In vivo assays for 15-PGDH expression or 15-PGDH activity, e.g., ligands, agonists, antagonists, and their homologs and mimetics. The term modulator ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM347375(US10301320, ID SW208080 | US10869871, ID # SW20808...)
Affinity DataIC50:  2.61nMAssay Description:It is not clearly defined.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM347375(US10301320, ID SW208080 | US10869871, ID # SW20808...)
Affinity DataIC50:  2.61nMAssay Description:Assays were done by measuring the transfer of tritium from 15(S)-[15-3H] PGE2 to glutamate (at 1 μM PGE2 substrate), or by direct fluorescence m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM347375(US10301320, ID SW208080 | US10869871, ID # SW20808...)
Affinity DataIC50:  2.64nMAssay Description:This Example provides data on a group of structural analogues of SW033291. Data provided includes level of induction of a 15-PGDH-luciferase fusion g...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent