BDBM347615 4-({3-[4-Chloro-2-(trifluoromethyl)phenyl]piperidin-1-yl}carbonyl)-1-methyl-1H-pyrazol-3-amine::US9790201, 100::US9790201, 118::US9790201, 119

SMILES Cn1cc(C(=O)N2CCCC(C2)c2ccc(Cl)cc2C(F)(F)F)c(N)n1

InChI Key InChIKey=YJVFDAGBSXBSMO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 347615   

TargetProkineticin receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM347615(4-({3-[4-Chloro-2-(trifluoromethyl)phenyl]piperidi...)
Affinity DataIC50:  540nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProkineticin receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM347615(4-({3-[4-Chloro-2-(trifluoromethyl)phenyl]piperidi...)
Affinity DataIC50:  330nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProkineticin receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM347615(4-({3-[4-Chloro-2-(trifluoromethyl)phenyl]piperidi...)
Affinity DataIC50: >1.00E+4nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent