BDBM347659 2-[2-[2-methoxy-4-[1-methyl-4-(4-pyridyl)pyrazol-3-yl]phenyl]ethynyl]-6-methylpyridine::US9790203, Example 32
SMILES COc1cc(ccc1C#Cc1cccc(C)n1)-c1nn(C)cc1-c1ccncc1
InChI Key InChIKey=VMLCBKKFIWPXDQ-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 347659
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Therachem Research Medilab
Curated by ChEMBL
Therachem Research Medilab
Curated by ChEMBL
Affinity DataIC50: <100nMAssay Description:Inhibition of recombinant PDE10A (unknown origin) using cAMP/cGMP as substrate incubated for 60 mins by HTRF assayMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Therachem Research Medilab
Curated by ChEMBL
Therachem Research Medilab
Curated by ChEMBL
Affinity DataIC50: <100nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair