BDBM347719 5-(2-Chloro-4-methylsulfonylphenyl)-4-(4-chlorophenoxy)-1H-pyrazole::US9790217, 42

SMILES CS(=O)(=O)c1ccc(-c2[nH]ncc2Oc2ccc(Cl)cc2)c(Cl)c1

InChI Key InChIKey=FVUWWINWWFWXRD-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 347719   

TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM347719(5-(2-Chloro-4-methylsulfonylphenyl)-4-(4-chlorophe...)
Affinity DataEC50:  0.345nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM347719(5-(2-Chloro-4-methylsulfonylphenyl)-4-(4-chlorophe...)
Affinity DataEC50:  0.0300nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent