BDBM348045 US9790221, Compound 253
SMILES Cc1nnc(s1)-c1cnc(nc1NC1CCCN(CC1)S(C)(=O)=O)-c1cccc(c1)-c1cnn(C)c1
InChI Key InChIKey=VIOGMLCMHMBTBR-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 348045
Affinity DataIC50: <100nMAssay Description:IRAK4 is a human purified recombinant enzyme (His-TEV-IRAK1 (194-712). IRAK4 hydrolyses ATP, autophosphorylates and phosphorylates a Serine/Threonine...More data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 1 [194-712](Homo sapiens (Human))
Merck Patent
US Patent
Merck Patent
US Patent
Affinity DataIC50: <100nMAssay Description:IRAK1 is a human purified recombinant enzyme (His-TEV-IRAK1 (194-712)). In this assay, IRAK-1 hydrolyses ATP and autophosphorylates. Measurement of I...More data for this Ligand-Target Pair