BDBM348641 1-[3-[(1R,3S,4R)-2-Oxa-5-azabicyclo[2.2.1]heptan-3-yl]phenyl]-3-[4-(trifluoromethyl)phenyl]urea::US9790230, Example 3

SMILES FC(F)(F)c1ccc(NC(=O)Nc2cccc(c2)[C@@H]2O[C@H]3CN[C@@H]2C3)cc1

InChI Key InChIKey=ZNELJINCYKHWAC-ZACQAIPSSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 348641   

TargetTrace amine-associated receptor 1(Rattus norvegicus (Rat))
Hoffmann-La Roche

US Patent
LigandPNGBDBM348641(1-[3-[(1R,3S,4R)-2-Oxa-5-azabicyclo[2.2.1]heptan-3...)
Affinity DataIC50:  2.90nMAssay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM348641(1-[3-[(1R,3S,4R)-2-Oxa-5-azabicyclo[2.2.1]heptan-3...)
Affinity DataIC50:  986nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent