BDBM349127 Cyclopropanecarboxylic acid (5-{4-[(2,6-difluoro- phenylamino)-methyl]- phenyl}-[1,2,4]triazolo[1,5- a]pyridin-2-yl)-amide::US10206907, Compound 246
SMILES Fc1cccc(F)c1NCc1ccc(cc1)-c1cccc2nc(NC(=O)C3CC3)nn12
InChI Key InChIKey=LTWWRRBLNNRLQF-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 349127
Affinity DataIC50: <100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:Recombinant human JAK2 catalytic domain (amino acids 808-1132; catalog number PV4210) was purchased from Invitrogen. 0.025 mU of JAK2 was incubated w...More data for this Ligand-Target Pair