BDBM349226 (4R)-4-methyl-6-[1-methyl-3-(1-methylpyrazol-4-yl)indazol-4-yl]-1,3,4,5-tetrahydro-1,5-benzodiazepin-2-one::US10206931, Example 33
SMILES CN\C=C(/C=N)C(=N)c1cc(ccc1NC)-c1cccc2NC(=O)C[C@@H](C)Nc12
InChI Key InChIKey=ZEGMWBOLKFYTOC-PEAVLORHSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 349226
Affinity DataIC50: 2.57E+3nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair