BDBM349275 (4R)-6-(3-cyclopropyl-1-methyl-indazol-5-yl)-4,9-dimethyl-1,3,4,5-tetrahydro-1,5-benzodiazepin-2-one::US10206931, Example 82
SMILES CNc1ccc(cc1C(=N)C1CC1)-c1ccc(C)c2NC(=O)C[C@@H](C)Nc12
InChI Key InChIKey=LAJSFXKVIQBXCH-CYBMUJFWSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 349275
Affinity DataIC50: 3.65E+3nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Affinity DataIC50: 99nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair