BDBM349279 (2R)-9-(3-cyclopropyl-1-methyl-indazol-5-yl)-6-methoxy-2-methyl-1,2,3,5-tetrahydro-1,5-benzodiazepin-4-one::US10206931, Example 86
SMILES CNc1ccc(cc1C(=N)C1CC1)-c1ccc(OC)c2NC(=O)C[C@@H](C)Nc12
InChI Key InChIKey=REBDYEMTSBYMEH-GFCCVEGCSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 349279
Affinity DataIC50: 2.78E+3nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Affinity DataIC50: 46nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair