BDBM349485 US10206931, Example 293::methyl-6-(1-

SMILES CN\C=C(/C=N)c1ccc2N(CC[C@@H](C)c2c1)c1cccc2NC(=O)C[C@@H](C)Nc12

InChI Key InChIKey=AWKZKSSSAAVVMA-HYSYFVHKSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 349485   

TargetBromodomain-containing protein 4 [42-168](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM349485(US10206931, Example 293 | methyl-6-(1-)
Affinity DataIC50:  9.02E+3nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCREB-binding protein(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM349485(US10206931, Example 293 | methyl-6-(1-)
Affinity DataIC50:  35nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent