BDBM349504 (4R)-4-methyl-6-[3-(1-methylpyrazol-1-yl)-8-isoquinolyl]-1,3,4,5-tetrahydro-1,5-benzodiazepin-2-one::US10206931, Example 312
SMILES CN\C=C(/C=N)c1cc2cccc(-c3cccc4NC(=O)C[C@@H](C)Nc34)c2cn1
InChI Key InChIKey=GPMVFHQNUQZTJP-DDTSFCPISA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 349504
Affinity DataIC50: 4.05E+3nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair