BDBM349571 US10207991, Ex. Cpd. No. 95::US10611728, Example Compound 95::US11691947, Example 95

SMILES CC(C)(C)Oc1cc(CCC(C)(C)n2cc3ccc(cc3c2)S(C)(=O)=O)ccc1O

InChI Key InChIKey=JYKBADJZSNFXOC-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 349571   

TargetSigma intracellular receptor 2(Homo sapiens (Human))
Cognition Therapeutics

US Patent
LigandPNGBDBM349571(US10207991, Ex. Cpd. No. 95 | US10611728, Example ...)
Affinity DataKi:  100nMAssay Description:The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Cognition Therapeutics

US Patent
LigandPNGBDBM349571(US10207991, Ex. Cpd. No. 95 | US10611728, Example ...)
Affinity DataKi:  100nMAssay Description:The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSigma intracellular receptor 2(Homo sapiens (Human))
Cognition Therapeutics

US Patent
LigandPNGBDBM349571(US10207991, Ex. Cpd. No. 95 | US10611728, Example ...)
Affinity DataKi:  100nMAssay Description:Radioligand binding assays for Sigma-1 receptors and Sigma-2 receptors were carried out by a commercial contract research organization. For Sigma-1 b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSigma intracellular receptor 2(Homo sapiens (Human))
Cognition Therapeutics

US Patent
LigandPNGBDBM349571(US10207991, Ex. Cpd. No. 95 | US10611728, Example ...)
Affinity DataKi:  100nMAssay Description:Radioligand binding assays for Sigma-1 receptors and Sigma-2 receptors were carried out by a commercial contract research organization. For Sigma-1 b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent