BDBM349573 US10207991, Ex. Cpd. No. 98::US10611728, Example Compound 98::US11691947, Example 98

SMILES COc1cccc(CCC(C)(C)N2Cc3cccc(C(=O)N4CCNCC4)c3C2)c1

InChI Key InChIKey=LJSPHZLEKKQLGW-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 349573   

TargetSigma intracellular receptor 2(Homo sapiens (Human))
Cognition Therapeutics

US Patent
LigandPNGBDBM349573(US10207991, Ex. Cpd. No. 98 | US10611728, Example ...)
Affinity DataKi:  1.00E+4nMAssay Description:The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Cognition Therapeutics

US Patent
LigandPNGBDBM349573(US10207991, Ex. Cpd. No. 98 | US10611728, Example ...)
Affinity DataKi:  1.00E+4nMAssay Description:The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSigma intracellular receptor 2(Homo sapiens (Human))
Cognition Therapeutics

US Patent
LigandPNGBDBM349573(US10207991, Ex. Cpd. No. 98 | US10611728, Example ...)
Affinity DataKi:  1.00E+4nMAssay Description:Radioligand binding assays for Sigma-1 receptors and Sigma-2 receptors were carried out by a commercial contract research organization. For Sigma-1 b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSigma intracellular receptor 2(Homo sapiens (Human))
Cognition Therapeutics

US Patent
LigandPNGBDBM349573(US10207991, Ex. Cpd. No. 98 | US10611728, Example ...)
Affinity DataKi:  1.00E+4nMAssay Description:Radioligand binding assays for Sigma-1 receptors and Sigma-2 receptors were carried out by a commercial contract research organization. For Sigma-1 b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent