BDBM349580 US10207991, Ex. Cpd. No. 105::US10611728, Example Compound 105::US11691947, Example 105

SMILES CC(C)(CCc1ccc(Cl)cc1)N1Cc2cccc(C(=O)N3CCNCC3)c2C1

InChI Key InChIKey=XCMFAFQSFPHNPQ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 349580   

TargetSigma intracellular receptor 2(Homo sapiens (Human))
Cognition Therapeutics

US Patent
LigandPNGBDBM349580(US10207991, Ex. Cpd. No. 105 | US10611728, Example...)
Affinity DataKi:  180nMAssay Description:The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Cognition Therapeutics

US Patent
LigandPNGBDBM349580(US10207991, Ex. Cpd. No. 105 | US10611728, Example...)
Affinity DataKi:  180nMAssay Description:The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSigma intracellular receptor 2(Homo sapiens (Human))
Cognition Therapeutics

US Patent
LigandPNGBDBM349580(US10207991, Ex. Cpd. No. 105 | US10611728, Example...)
Affinity DataKi:  180nMAssay Description:Radioligand binding assays for Sigma-1 receptors and Sigma-2 receptors were carried out by a commercial contract research organization. For Sigma-1 b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSigma intracellular receptor 2(Homo sapiens (Human))
Cognition Therapeutics

US Patent
LigandPNGBDBM349580(US10207991, Ex. Cpd. No. 105 | US10611728, Example...)
Affinity DataKi:  180nMAssay Description:Radioligand binding assays for Sigma-1 receptors and Sigma-2 receptors were carried out by a commercial contract research organization. For Sigma-1 b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent