BDBM349789 2-{[(2S)-4-{6-[(4-cyano-2-fluorobenzyl)oxy]pyridin-2-yl}-2-methylpiperazin-1-yl]methyl}-1-[(3R)-tetrahydrofuran-3-ylmethyl]-1H-benzimidazole-6-carboxylic acid::US10208019, Example 10A-59

SMILES C[C@H]1CN(CCN1Cc1nc2ccc(cc2n1C[C@H]1CCOC1)C(O)=O)c1cccc(OCc2ccc(cc2F)C#N)n1

InChI Key InChIKey=UTGCMTZPWNPDAN-JTHBVZDNSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 349789   

TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM349789(2-{[(2S)-4-{6-[(4-cyano-2-fluorobenzyl)oxy]pyridin...)
Affinity DataEC50:  84nMAssay Description:GLP-1R-mediated agonist activity was determined with a cell-based functional assay utilizing an HTRF (Homogeneous Time-Resolved Fluorescence) cAMP de...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM349789(2-{[(2S)-4-{6-[(4-cyano-2-fluorobenzyl)oxy]pyridin...)
Affinity DataEC50:  4.70nMAssay Description:GLP-1R-mediated agonist activity was determined with a cell-based functional assay utilizing an HTRF (Homogeneous Time-Resolved Fluorescence) cAMP de...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent