BDBM34990 benzothienopyrimidinone deriv., 6g

SMILES OC1CCCN(Cc2nc3c4cc(Cl)ccc4sc3c(=O)[nH]2)C1

InChI Key InChIKey=SAVHQKIDKMSOHS-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 34990   

TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM34990(benzothienopyrimidinone deriv., 6g)
Affinity DataKi:  33nM ΔG°:  -10.1kcal/molepH: 7.5 T: 2°CAssay Description:In 384-well v-bottom polypropylene plates, compound (2% DMSO) was mixed with Pim kinase and peptide substrate, followed by immediate initiation with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM34990(benzothienopyrimidinone deriv., 6g)
Affinity DataKi: >1.42E+3nM ΔG°: >-7.97kcal/moleT: 2°CAssay Description:In 384-well v-bottom polypropylene plates, compound (2% DMSO) was mixed with Pim kinase and peptide substrate, followed by immediate initiation with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed