BDBM350005 1-((4-(5-amino-6-(1- (3,5- dimethoxyphenyl)-6- oxo-1,6- dihydropyridazin-3- yl)pyrazin-2-yl)-1H- pyrazol-1- yl)methyl)cyclopropane- 1-carbonitrile::US10208024, Example 4::US10766881, Example 4
SMILES COc1cc(OC)cc(c1)-n1nc(ccc1=O)-c1nc(cnc1N)-c1cnn(CC2(CC2)C#N)c1
InChI Key InChIKey=BTGLYCHFNHKNDV-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 350005
Affinity DataIC50: 15.4nMAssay Description:FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphor...More data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMAssay Description:FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphor...More data for this Ligand-Target Pair
Affinity DataIC50: 15.4nMAssay Description:To measure FGFR1 kinase activity, 200 pM His-tagged recombinant human FGFR1 catalytic domain (amino acids 308-731) (Life Technologies Cat. No. PR4660...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphor...More data for this Ligand-Target Pair