BDBM35010 benzothienopyrimidinone deriv., 11b

SMILES CC(C)c1ccc2sc3c(nc(CN(C)C)[nH]c3=O)c2c1

InChI Key InChIKey=BUZDEHLSGHZEBZ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35010   

TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM35010(benzothienopyrimidinone deriv., 11b)
Affinity DataKi:  20nM ΔG°:  -10.4kcal/molepH: 7.5 T: 2°CAssay Description:In 384-well v-bottom polypropylene plates, compound (2% DMSO) was mixed with Pim kinase and peptide substrate, followed by immediate initiation with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM35010(benzothienopyrimidinone deriv., 11b)
Affinity DataKi:  21nM ΔG°:  -10.5kcal/moleT: 2°CAssay Description:In 384-well v-bottom polypropylene plates, compound (2% DMSO) was mixed with Pim kinase and peptide substrate, followed by immediate initiation with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed