BDBM350146 (1S,3R)-3-[8-amino-1-(4- {(1S)-1-hydroxy-1-[3- (trifluoromethyl)phenyl] ethyl}phenyl)imidazo[1,5- a]pyrazin-3-yl]-1-(1- methylethyl)cyclohexane- carboxylic acid::US10208047, Example 14
SMILES CC(C)[C@@]1(CCC[C@H](C1)c1nc(-c2ccc(cc2)[C@](C)(O)c2cccc(c2)C(F)(F)F)c2c(N)nccn12)C(O)=O
InChI Key InChIKey=AAPXQEUSUAUPKI-LYWBODIJSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 350146
Affinity DataIC50: 1.00E+3nMAssay Description:BTK enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (Time-resolved fluorescence resonance energy transfer) assay...More data for this Ligand-Target Pair